Arsenic-exposed Keratinocytes Exhibit Differential microRNAs Expression Profile; Potential Implication of miR-21, miR-200a and miR-141 in Melanoma Pathway
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چکیده
منابع مشابه
Evaluation of miR-141, miR-200c, miR-30b Expression and Clinicopathological Features of Bladder Cancer
Bladder cancer (BC) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. MiRNAs expression has noticeable role in bladder tumorigenesis. The purpose of this study was to assess miR-200c, miR-30b and miR-141 in tissue samples of patients with BC and healthy adjacent tissue samples and their association with muscle invasion, grade...
متن کاملDifferential expression of miR-1297, miR-3191-5p, miR-4435, and miR-4465 in malignant and benign breast tumors
Objective(s): MicroRNAs (miRs) are a class of small non-coding RNAs which are associated with tumor growth and progression. In the present study, we assessed the expression of selected miRs in malignant, benign, and adjacent normal breast tissues. Materials and Methods: The expression of miR-1297, miR-3191-5P, miR-4435, and miR-4465 were...
متن کاملoptimization of extraction and amplification of micrornas (mir-21, mir-141 and mir-205) in urine samples of patients with bladder cancer
objective: the current methods for bladder cancer diagnosis suffer from low sensitivity and specificity. therefore, finding a novel tumor markers with high specificity and sensitivity is of great interest. micrornas (mirna, mir) are small endogenously-produced, non-coding rnas with an important role in regulating gene expression. recent studies show that mirnas expression profiles represent sig...
متن کاملMiR-21 Expression in Wilms’ Tumor
Background and Objective: Wilms’ tumor (WT) is the most common genitourinary tract tumor in children. MicroRNAs (miRNAs) are small non-coding RNAs; their role in the pathogenesis of many types of human cancers has been identified. We aimed to evaluate the expression of miR-21, a well-known oncomir, in WT tissue samples which is a very common urinary tract malignancy in children...
متن کاملevaluation of mir-141, mir-200c, mir-30b expression and clinicopathological features of bladder cancer
bladder cancer (bc) ranks the second most common genitourinary tract malignant tumor with high mortality and 70% recurrence rate worldwide. mirnas expression has noticeable role in bladder tumorigenesis. the purpose of this study was to assess mir-200c, mir-30b and mir-141 in tissue samples of patients with bc and healthy adjacent tissue samples and their association with muscle invasion, grade...
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ژورنال
عنوان ژورنال: Clinical Cancer Drugs
سال: 2015
ISSN: 2212-697X
DOI: 10.2174/2212697x02666150629174704